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Calcitonin Gene-Related Peptide (CGRP) Mechanisms

- Focus on Migraine
Engelsk Paperback

Calcitonin Gene-Related Peptide (CGRP) Mechanisms

- Focus on Migraine
Engelsk Paperback
Tjek vores konkurrenters priser
This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine.  The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention. 
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This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine.  The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention. 
Produktdetaljer
Sprog: Engelsk
Sider: 192
ISBN-13: 9783030214562
Indbinding: Paperback
Udgave:
ISBN-10: 3030214567
Udg. Dato: 11 sep 2020
Længde: 0mm
Bredde: 155mm
Højde: 235mm
Forlag: Springer Nature Switzerland AG
Oplagsdato: 11 sep 2020
Forfatter(e):
Forfatter(e)


Kategori Smerter og smertebehandling


ISBN-13 9783030214562


Sprog Engelsk


Indbinding Paperback


Sider 192


Udgave


Længde 0mm


Bredde 155mm


Højde 235mm


Udg. Dato 11 sep 2020


Oplagsdato 11 sep 2020


Forlag Springer Nature Switzerland AG

Kategori sammenhænge