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Hematopoietic Stem Cell Transplantation
Engelsk
Bogcover for Hematopoietic Stem Cell Transplantation af , 9780367398316
Specifikationer
Sprog:
Engelsk
Sider:
624
ISBN-13:
9780367398316
Indbinding:
Paperback
ISBN-10:
0367398311
Kategori:
Udg. Dato:
1 nov 2019
Størrelse i cm:
24,6 x 17,4
Oplagsdato:
1 nov 2019

Hematopoietic Stem Cell Transplantation

Engelsk
Paperback 2019
Format:

Bog beskrivelse
This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more.
Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life.
Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation
  • summarizes current understanding and development of clinical allogeneic HSC transplantation
  • discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation
  • considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors
  • details detection of bone marrow contamination by tumor cells and removal procedures
  • focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors
  • explores the effects of growth factor administration and leukapheresis on PB stem cell donors
  • shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use
  • reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells
  • employs automated fluorescence image cytometry to study early HSC behavior following seeding
    Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,











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    Specifikationer
    Sprog:
    Engelsk
    Sider:
    624
    ISBN-13:
    9780367398316
    Indbinding:
    Paperback
    ISBN-10:
    0367398311
    Kategori:
    Udg. Dato:
    1 nov 2019
    Størrelse i cm:
    24,6 x 17,4
    Oplagsdato:
    1 nov 2019
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