Store besparelser
Hurtig levering
Gemte
Log ind
0
Kurv
Kurv
Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis
Engelsk Paperback
Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis
Engelsk Paperback

907 kr
Tilføj til kurv
Sikker betaling
6 - 8 hverdage

Om denne bog
There is now evidence that irreversible brain damage accumulates very early in the course of multiple sclerosis. This book reviews the main neurobiological, magnetic resonance imaging, and clinical aspects of the early phases of the dis­ ease. Mechanisms ofirreversible axonal damage and the role played by the inter­ action of glia and the axon are highlighted. In contrast to what was believed for a long time, the sufficient availability of oligodendrocyte precursor cells to promote remyelination in acute lesions has now been demonstrated. For reasons not understood, this remyelination process fails or does not start, particularly in the chronic stages ofthe disease. These findings emphasize the importance of the "milieu" changes induced by an inflammatory process in limiting remyelination. However, first indications are that part of this inflammatory process may have a neuroprotective effect. Pathological studies in multiple sclerosis have now clearly demonstrated that destructive processes may be followed by recovery phases in such a way that myelin may be morphologically and functionally reconstituted. These findings provide the rationale for early treatment and emphasize the importance of clinical trials in early multiple sclerosis. Early treatment is one of the most important aspects in multiple sclerosis today.
Product detaljer
Sprog:
Engelsk
Sider:
199
ISBN-13:
9788847021716
Indbinding:
Paperback
Udgave:
ISBN-10:
8847021715
Kategori:
Udg. Dato:
28 sep 2012
Længde:
0mm
Bredde:
155mm
Højde:
235mm
Forlag:
Springer Verlag
Oplagsdato:
28 sep 2012
Forfatter(e):
Kategori sammenhænge