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Advanced Glycation End-Products

- Sources and Effects
Engelsk Paperback

Advanced Glycation End-Products

- Sources and Effects
Engelsk Paperback
Tjek vores konkurrenters priser
This book attempts to describe the role of advanced glycation end-products, particularly dietary advanced glycation end-products, in the pathological expansion of adipose tissue as well as their implications in the development of obesity associated complications. The effects of advanced glycation end-products on vasculature and their pathological implications are also described, focusing on the epigenetic mechanisms (particularly that of miRNA) modulating their effects. The authors summarize the information available on the impact of hyperglycemia on the influencing factors of non-enzymatic glycosylation, the formation of advanced glycation end-products, and the role of advanced glycation end-products and their specific receptors in diabetes. The role of advanced glycation end-products to diabetic complications is examined in conjunction with the protective role of the endogenous secretory receptor for advanced glycation end-products (esRAGE) and the therapeutic interveentions that would mimic esRAGE activity. In closing, poly-L-lysine modified with advanced glycation end-products is prepared and used as an antigen to generate a single-chain fragment variable monoclonal antibody (scFv mAb) through phage display technology.
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This book attempts to describe the role of advanced glycation end-products, particularly dietary advanced glycation end-products, in the pathological expansion of adipose tissue as well as their implications in the development of obesity associated complications. The effects of advanced glycation end-products on vasculature and their pathological implications are also described, focusing on the epigenetic mechanisms (particularly that of miRNA) modulating their effects. The authors summarize the information available on the impact of hyperglycemia on the influencing factors of non-enzymatic glycosylation, the formation of advanced glycation end-products, and the role of advanced glycation end-products and their specific receptors in diabetes. The role of advanced glycation end-products to diabetic complications is examined in conjunction with the protective role of the endogenous secretory receptor for advanced glycation end-products (esRAGE) and the therapeutic interveentions that would mimic esRAGE activity. In closing, poly-L-lysine modified with advanced glycation end-products is prepared and used as an antigen to generate a single-chain fragment variable monoclonal antibody (scFv mAb) through phage display technology.
Produktdetaljer
Sprog: Engelsk
Sider: 144
ISBN-13: 9781536175479
Indbinding: Paperback
Udgave:
ISBN-10: 1536175471
Kategori: Biokemi
Udg. Dato: 1 jun 2020
Længde: 0mm
Bredde: 0mm
Højde: 0mm
Forlag: Nova Science Publishers Inc
Oplagsdato: 1 jun 2020
Forfatter(e):
Forfatter(e)


Kategori Biokemi


ISBN-13 9781536175479


Sprog Engelsk


Indbinding Paperback


Sider 144


Udgave


Længde 0mm


Bredde 0mm


Højde 0mm


Udg. Dato 1 jun 2020


Oplagsdato 1 jun 2020


Forlag Nova Science Publishers Inc

Kategori sammenhænge