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  1. Bog
  2. Biovidenskab: generelt
  3. Genetik (ikke-medicinsk)

Gene Delivery

- Methods and Applications
Engelsk Paperback

Gene Delivery

- Methods and Applications
Engelsk Paperback
Tjek vores konkurrenters priser
Gene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well as a snapshot of the advances and technical challenges yet to be addressed. Next, a variety of gene delivery systems including physical transfection techniques, virus-based delivery vectors, chemically engineered delivery systems and bio-inspired vehicles are reviewed and their strengths, shortcomings and biomedical applications are discussed. Selfish DNA called transposons capable of cutting out and pasting into the host genome are active throughout the phylogenetic kingdoms. Researchers have repurposed natural transposons for use in delivering a gene-of-interest, enabling for the study of a large and growing list of preclinical gene therapy applications. As such, the authors discuss the past achievements and future challenges of this early-stage technology. The closing chapter introduces cell-penetrating peptides as an efficient tool for DNA transfection. HR9, a designed cell-penetrating peptides, containing nona-arginine flanked by cysteine and penta-histidine displayed a high penetrating ability in mammalian cells.
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Tjek vores konkurrenters priser
Normalpris
kr 923
Fragt: 39 kr
6 - 8 hverdage
20 kr
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God 4 anmeldelser på
Tjek vores konkurrenters priser
Gene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells. In addition, an update on ongoing and completed clinical studies with engineered mesenchymal stromal cells will be provided, as well as a snapshot of the advances and technical challenges yet to be addressed. Next, a variety of gene delivery systems including physical transfection techniques, virus-based delivery vectors, chemically engineered delivery systems and bio-inspired vehicles are reviewed and their strengths, shortcomings and biomedical applications are discussed. Selfish DNA called transposons capable of cutting out and pasting into the host genome are active throughout the phylogenetic kingdoms. Researchers have repurposed natural transposons for use in delivering a gene-of-interest, enabling for the study of a large and growing list of preclinical gene therapy applications. As such, the authors discuss the past achievements and future challenges of this early-stage technology. The closing chapter introduces cell-penetrating peptides as an efficient tool for DNA transfection. HR9, a designed cell-penetrating peptides, containing nona-arginine flanked by cysteine and penta-histidine displayed a high penetrating ability in mammalian cells.
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Se mere i:
Produktdetaljer
Sprog: Engelsk
Sider: 207
ISBN-13: 9781536162684
Indbinding: Paperback
Udgave:
ISBN-10: 153616268X
Kategori: Genetik (ikke-medicinsk)
Udg. Dato: 1 okt 2019
Længde: 18mm
Bredde: 231mm
Højde: 153mm
Forlag: Nova Science Publishers Inc
Oplagsdato: 1 okt 2019
Forfatter(e):
Forfatter(e)

Kategori Genetik (ikke-medicinsk)

ISBN-13 9781536162684

Sprog Engelsk

Indbinding Paperback

Sider 207

Udgave

Længde 18mm

Bredde 231mm

Højde 153mm

Udg. Dato 1 okt 2019

Oplagsdato 1 okt 2019

Forlag Nova Science Publishers Inc

Kategori sammenhænge