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Glutathione S-Transferases
- Structure, Functions and Clinical Aspects
Engelsk Paperback
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Glutathione S-Transferases

- Structure, Functions and Clinical Aspects
Engelsk Paperback

774 kr
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Om denne bog
Glutathione S-transferase (GST) isoenzymes are an important superfamily of proteins that are present in homodimer or heterodimer structures. The isoenzymes included in this superfamily are involved in endobiotic and xenobiotic detoxification systems in animals, plants and microorganisms. This compilation focuses on the importance of functional aspects of polymorphic variants in different populations so the risk genotypes can be identified as indicators of disease susceptibility. Genetic studies will help to develop prognostic biomarkers for early prediction and risk assessment in patients, and enable clinicians to develop personalized treatment regimens. The authors examine the different kinds of reactive oxygen species and reactive species which act as carcinogens and cause damage to DNA, RNA, proteins and lipids, thereby resulting in human disease like bladder cancer. Also reviewed is the association of GST's common genetic variants with the development of infertility (failure to establish a clinical pregnancy after 12 months of regular, unprotected sexual intercourse) in women and in men.
Product detaljer
Sprog:
Engelsk
Sider:
142
ISBN-13:
9781536181883
Indbinding:
Paperback
Udgave:
ISBN-10:
1536181889
Udg. Dato:
1 sep 2020
Længde:
0mm
Bredde:
0mm
Højde:
0mm
Forlag:
Nova Science Publishers Inc
Oplagsdato:
1 sep 2020
Forfatter(e):
Oversætter:
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