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Mannose-Binding Lectin in the Innate Immune System
Engelsk Paperback
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Mannose-Binding Lectin in the Innate Immune System

Engelsk Paperback

462 kr
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Om denne bog
Mannose-binding lectin (MBL) is a plasma protein with an important role in the innate immune system. MBL recognises pathogens through carbohydrate structures present on the surface of a range of pathogenic organisms including viruses, bacteria, fungi and protozoans. These structures may be referred to as pathogen-associated molecular patterns (PAMPs). After binding to PAMPs, MBL promotes C1- and antibody-independent activation of complement, leading to complement-mediated killing and/or phagocytosis. MBL is also known to modulate the secretion of cytokines from macrophages and to mediate the clearance of apoptotic cells as such playing a role in the inflammatory response. This book summarises the actual understanding of human MBL biology and introduces the general aspects of the structure, function and genetics of MBL, as well as an analysis of the role of MBL in the predisposition to clinically relevant diseases.
Product detaljer
Sprog:
Engelsk
Sider:
90
ISBN-13:
9781606927168
Indbinding:
Paperback
Udgave:
ISBN-10:
1606927167
Kategori:
Udg. Dato:
28 maj 2009
Længde:
8mm
Bredde:
176mm
Højde:
194mm
Forlag:
Nova Science Publishers Inc
Oplagsdato:
28 maj 2009
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