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  3. Molekylærbiologi

Myths And Verities In Protein Folding Theories

Af: Arieh Ben-naim Engelsk Hardback

Myths And Verities In Protein Folding Theories

Af: Arieh Ben-naim Engelsk Hardback
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This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.

It all started from the misinterpretation of Schellman's experiments which were carried out in the mid-1950s, and which were later encapsulated by the so-called "Hydrogen-bond inventory argument." As a result, hydrogen bonding was ignored in protein folding; along with that a whole repertoire of other possible hydrophilic effects were not even considered. Against this background the hydrophobic effects, as suggested by Kauzmann, became the single most important effects in protein folding.

In addition, as a result of the misinterpretation of Anfinsen's hypothesis, as well as misunderstanding of the Second Law, people made futile attempts to search for the structure of proteins in the global minimum of either the Energy, or the Gibbs Energy Landscape.

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This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.

It all started from the misinterpretation of Schellman's experiments which were carried out in the mid-1950s, and which were later encapsulated by the so-called "Hydrogen-bond inventory argument." As a result, hydrogen bonding was ignored in protein folding; along with that a whole repertoire of other possible hydrophilic effects were not even considered. Against this background the hydrophobic effects, as suggested by Kauzmann, became the single most important effects in protein folding.

In addition, as a result of the misinterpretation of Anfinsen's hypothesis, as well as misunderstanding of the Second Law, people made futile attempts to search for the structure of proteins in the global minimum of either the Energy, or the Gibbs Energy Landscape.

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Se mere i:
Produktdetaljer
Sprog: Engelsk
Sider: 448
ISBN-13: 9789814725989
Indbinding: Hardback
Udgave:
ISBN-10: 9814725986
Kategori: Molekylærbiologi
Udg. Dato: 24 feb 2016
Længde: 24mm
Bredde: 237mm
Højde: 159mm
Forlag: World Scientific Publishing Co Pte Ltd
Oplagsdato: 24 feb 2016
Forfatter(e): Arieh Ben-naim
Forfatter(e) Arieh Ben-naim

Kategori Molekylærbiologi

ISBN-13 9789814725989

Sprog Engelsk

Indbinding Hardback

Sider 448

Udgave

Længde 24mm

Bredde 237mm

Højde 159mm

Udg. Dato 24 feb 2016

Oplagsdato 24 feb 2016

Forlag World Scientific Publishing Co Pte Ltd

Kategori sammenhænge