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Pertussis Infection and Vaccines
- Advances in Microbiology, Infectious Diseases and Public Health Volume 12
Engelsk Hardback
Pertussis Infection and Vaccines
- Advances in Microbiology, Infectious Diseases and Public Health Volume 12
Engelsk Hardback

907 kr
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Om denne bog

This book provides a comprehensive overview of pertussis - also known as whooping cough. The first part discusses the evolution the genus Bordetellae and the molecular epidemiology of B. pertussis, while the following chapters focus on the role of B. pertussis virulence factors in infection and disease and on the mechanisms of the immune response to infection and vaccination. The book also explores the prevention and control of the disease as well as its clinical management, with the finally section addressing vaccination, from improved immunization strategies to novel vaccines.

Pertussis remains one of the most poorly controlled vaccine-preventable diseases around the globe. Universal vaccination has dramatically reduced its incidence but has failed to bring it completely under control. In recent decades, changes in pertussis epidemiology have been noted, likely related to the use of acellular pertussis vaccines, which in many countries have replaced older-generation, whole-cell pertussis vaccines. Several years after their introduction, it is becoming apparent that immunity conferred by acellular vaccines wanes more rapidly than expected. Unlike whole-cell vaccines, acellular vaccines, while protecting against the disease, do not seem to prevent colonization and transmission. Increasing incidence among adolescents and adults makes them a reservoir for transmission to unimmunized infants, who in turn are at risk of severe disease and death.

This book is a valuable resource for researchers and clinicians in the field of medical microbiology, vaccine research and infectious diseases.

Product detaljer
Sprog:
Engelsk
Sider:
170
ISBN-13:
9783030332488
Indbinding:
Hardback
Udgave:
ISBN-10:
3030332489
Udg. Dato:
7 jan 2020
Længde:
19mm
Bredde:
263mm
Højde:
186mm
Forlag:
Springer Nature Switzerland AG
Oplagsdato:
7 jan 2020
Forfatter(e):
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