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Statistical Methods for Survival Trial Design
- With Applications to Cancer Clinical Trials Using R
Engelsk
Bogcover for Statistical Methods for Survival Trial Design af Jianrong Wu, 9780367734329
Specifikationer
Sprog:
Engelsk
Sider:
257
ISBN-13:
9780367734329
Indbinding:
Paperback
ISBN-10:
036773432X
Kategori:
Udg. Dato:
18 dec 2020
Størrelse i cm:
23,4 x 15,6
Oplagsdato:
18 dec 2020
Forfatter(e):

Statistical Methods for Survival Trial Design

- With Applications to Cancer Clinical Trials Using R
Engelsk
Paperback 2020
Format:

Bog beskrivelse

Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint. Traditional cancer trial designs with time-to-event endpoints are often limited to the exponential model or proportional hazards model. In practice, however, those model assumptions may not be satisfied for long-term survival trials.

This book is the first to cover comprehensively the many newly developed methodologies for survival trial design, including trial design under the Weibull survival models; extensions of the sample size calculations under the proportional hazard models; and trial design under mixture cure models, complex survival models, Cox regression models, and competing-risk models. A general sequential procedure based on the sequential conditional probability ratio test is also implemented for survival trial monitoring. All methodologies are presented with sufficient detail for interested researchers or graduate students.

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Specifikationer
Sprog:
Engelsk
Sider:
257
ISBN-13:
9780367734329
Indbinding:
Paperback
ISBN-10:
036773432X
Kategori:
Udg. Dato:
18 dec 2020
Størrelse i cm:
23,4 x 15,6
Oplagsdato:
18 dec 2020
Forfatter(e):
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