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Statistics in Toxicology Using R
Engelsk
Bogcover for Statistics in Toxicology Using R af Ludwig A. Hothorn, 9781032098135
Specifikationer
Sprog:
Engelsk
Sider:
252
ISBN-13:
9781032098135
Indbinding:
Paperback
ISBN-10:
1032098139
Udg. Dato:
30 jun 2021
Størrelse i cm:
25,4 x 17,8
Oplagsdato:
30 jun 2021
Forfatter(e):

Statistics in Toxicology Using R

Engelsk
Paperback 2021
Format:

Bog beskrivelse

The apparent contradiction between statistical significance and biological relevance has diminished the value of statistical methods as a whole in toxicology. Moreover, recommendations for statistical analysis are imprecise in most toxicological guidelines. Addressing these dilemmas, Statistics in Toxicology Using R explains the statistical analysis of selected experimental data in toxicology and presents assay-specific suggestions, such as for the in vitro micronucleus assay.

Mostly focusing on hypothesis testing, the book covers standardized bioassays for chemicals, drugs, and environmental pollutants. It is organized according to selected toxicological assays, including:

  • Short-term repeated toxicity studies
  • Long-term carcinogenicity assays
  • Studies on reproductive toxicity
  • Mutagenicity assays
  • Toxicokinetic studies

The book also discusses proof of safety (particularly in ecotoxicological assays), toxicogenomics, the analysis of interlaboratory studies and the modeling of dose-response relationships for risk assessment. For each toxicological problem, the author describes the statistics involved, matching data example, R code, and outcomes and their interpretation. This approach allows you to select a certain bioassay, identify the specific data structure, run the R code with the data example, understand the test outcome and interpretation, and replace the data set with your own data and run again. 

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Specifikationer
Sprog:
Engelsk
Sider:
252
ISBN-13:
9781032098135
Indbinding:
Paperback
ISBN-10:
1032098139
Udg. Dato:
30 jun 2021
Størrelse i cm:
25,4 x 17,8
Oplagsdato:
30 jun 2021
Forfatter(e):
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