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The CRISPR/Cas9 System
- Applications and Technology
Engelsk
Bogcover for The CRISPR/Cas9 System af , 9781536164268
Specifikationer
Sprog:
Engelsk
Sider:
180
ISBN-13:
9781536164268
Indbinding:
Paperback
ISBN-10:
1536164267
Udg. Dato:
30 aug 2019
Størrelse i cm:
15,4 x 22,8 x 1,6
Oplagsdato:
30 aug 2019

The CRISPR/Cas9 System

- Applications and Technology
Engelsk
Paperback 2019
Format:

Bog beskrivelse
This compilation focuses on the CRISPR/Cas9 system, a genome editing tool that has been hailed as the most profound molecular biology discovery in the past decade. By employing the natural process of bacterial immunity towards bacteriophages, the tool allows researchers to precisely excise and edit parts of the genetic sequence to modify them. The authors summarize the molecular pathogenesis of hepatocellular carcinoma, available treatments/drugs and their limitations, the landscape of CRISPR targeting hepatocellular carcinoma, limitations and potential targets in future. The closing review summarises the use of CRISPR/Cas9 gene editing in ophthalmology and focuses on the advancement of gene editing in the cornea. The majority of corneal dystrophies are the result an autosomal dominant inheritance pattern within the TGFBI gene, which presents an ideal model suited for a CRISPR/Cas9 knock out methodology.
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Specifikationer
Sprog:
Engelsk
Sider:
180
ISBN-13:
9781536164268
Indbinding:
Paperback
ISBN-10:
1536164267
Udg. Dato:
30 aug 2019
Størrelse i cm:
15,4 x 22,8 x 1,6
Oplagsdato:
30 aug 2019
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