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Toward a History of Epistemic Things

- Synthesizing Proteins in the Test Tube
Af: Hans-Jorg Rheinberger Engelsk Paperback

Toward a History of Epistemic Things

- Synthesizing Proteins in the Test Tube
Af: Hans-Jorg Rheinberger Engelsk Paperback
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In this powerful work of conceptual and analytical originality, the author argues for the primacy of the material arrangements of the laboratory in the dynamics of modern molecular biology. In a post-Kuhnian move away from the hegemony of theory, he develops a new epistemology of experimentation in which research is treated as a process for producing epistemic things.

A central concern of the book is the basic question of how novelty is generated in the empirical sciences. In addressing this question, the author brings French poststructuralist thinking—notably Jacques Derrida’s concepts of “différance” and “historiality”—to bear on the construction of epistemic things. Historiographical perspective shifts from the actors’ minds to their objects of manipulation.

These epistemological and historical issues are illuminated in a detailed case study of a particular laboratory, that of the oncologist and biochemist Paul C. Zamecnik and his colleagues, located in a specific setting—the Collis P. Huntington Memorial Hospital of Harvard University at the Massachusetts General Hospital of Boston. The author traces how, between 1945 and 1965, this group developed an experimental system for synthesizing proteins in the test tube that put Zamecnik’s research team at the forefront of those who led biochemistry into the era of molecular biology.

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In this powerful work of conceptual and analytical originality, the author argues for the primacy of the material arrangements of the laboratory in the dynamics of modern molecular biology. In a post-Kuhnian move away from the hegemony of theory, he develops a new epistemology of experimentation in which research is treated as a process for producing epistemic things.

A central concern of the book is the basic question of how novelty is generated in the empirical sciences. In addressing this question, the author brings French poststructuralist thinking—notably Jacques Derrida’s concepts of “différance” and “historiality”—to bear on the construction of epistemic things. Historiographical perspective shifts from the actors’ minds to their objects of manipulation.

These epistemological and historical issues are illuminated in a detailed case study of a particular laboratory, that of the oncologist and biochemist Paul C. Zamecnik and his colleagues, located in a specific setting—the Collis P. Huntington Memorial Hospital of Harvard University at the Massachusetts General Hospital of Boston. The author traces how, between 1945 and 1965, this group developed an experimental system for synthesizing proteins in the test tube that put Zamecnik’s research team at the forefront of those who led biochemistry into the era of molecular biology.

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Produktdetaljer
Sprog: Engelsk
Sider: 340
ISBN-13: 9780804727860
Indbinding: Paperback
Udgave:
ISBN-10: 0804727864
Kategori: Videnskabsfilosofi
Udg. Dato: 1 jul 1997
Længde: 2mm
Bredde: 235mm
Højde: 154mm
Forlag: Stanford University Press
Oplagsdato: 1 jul 1997
Forfatter(e): Hans-Jorg Rheinberger
Forfatter(e) Hans-Jorg Rheinberger

Kategori Videnskabsfilosofi

ISBN-13 9780804727860

Sprog Engelsk

Indbinding Paperback

Sider 340

Udgave

Længde 2mm

Bredde 235mm

Højde 154mm

Udg. Dato 1 jul 1997

Oplagsdato 1 jul 1997

Forlag Stanford University Press

Kategori sammenhænge